Which of the following MOST accurately describes an acute myocardial infarction?

A. Damage to the left ventricle following occlusion of the left coronary artery
B. Injury to a portion of the heart muscle secondary to atherosclerotic disease
C. Necrosis of a portion of the myocardium due to a prolonged lack of oxygen
D. Death of the myocardium secondary to spasm of a major coronary artery