if you were to reduce the extracellular concentration of potassium how would that impact mEPPs? my professor wrote the following: By reducing the extracellular concentration of K+, you would be increasing the concentration gradient therefore making the equilibrium potential of potassium more hyperpolarized (negative). This in turn would increase the driving force on potassium. Since the nAChRs are permeable to both sodium and potassium, this would produce a larger K+ efflux through the channel at lower membrane potentials, which would lead to a lower net influx, thereby reducing the size of mEPPS.
I am a bit confused about the wording, can someone explain?