GW is a 38 year old male with a past medical history which includes asthma, GERD, chronic lower back pain and HIV. Height: 5'9"; Weight: 72 kg; Cr 2.2 mg/dL His medications include: Genvoya, Pepcid AC, Symbicort, Proair (PRN), and naproxen (PRN). He has gone to the emergency department multiple times for back pain and has received prescriptions for Percocet. He has been purchasing Oxycontin from an acquaintance and takes it most days for relief of his back pain. Which of the following is true regarding his medications?
A. Pepcid AC should not be taken with Genvoya because of the elvitegravir component. He should stop using this and switch to Tums as needed.
B. Pepcid AC should not be taken with Genvoya because of the emtricitabine component. He should stop using this and switch to Tums as needed.
C. Use of Oxycontin with Genvoya puts the patient at increased risk of respiratory depression.
D. Based on his renal function, Genvoya should be discontinued and another regimen should be started.
E. The tenofovir component of Genvoya will increase risk of liver toxicity when given with naproxen