Medication most likely be prescribed to a patient with a mechanical valve is Medication to decrease the viscosity of the blood. If you have a mechanical valve (made of plastic, metal, or cloth), you will likely take a blood thinner for the rest of your life to keep blood clots from forming on your valve surfaces. If you have a biological valve (made of animal or human tissue), you need to take a blood thinner for a few weeks or months after surgery while your body adapts to your new valve. Your doctor will tell you when you can stop taking this medicine. Then you will likely take low-dose aspirin to prevent blood clots.