Let's take the worst case scenario. Suppose the list consists of
-2, - 4, - 5, - 8
The product of the first and the last integers is positive
-2 * -8 = 16 so that checks out.
There's an even number in the list so the result will be positive.
Not enough variety. Suppose the list is
1, - 2, - 4 , -5
The largest is 1 the smallest - 5. The result disobeys the first condition of the problem.
Any other list is trivial.
Answer: yes if those two conditions are met.