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The physical barrier of the skin and the mucus produced by the epithelial cells lining body cavities ____.​ release histamines​ comprise the innate immune system​ ​protect the body from infection by pathogens ​activate the complement system ​facilitate the production of antibodies

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The answer is protect the body from infection by pathogens

The physical barrier is made of epithelial cells, mostly will be keratinized to increase their sturdiness further. They will impede the pathogen physically by barricading the cells, makes the pathogen could not invade deeper part of the body. Histamine and antibodies should be the role of immune cells, not epithelial.