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Answer:
The role of CFTR is to build channels on the cell surface to enable the flow of chloride (Cl-). When the CFTR protein works properly, the balance of Cl-and fluid at the cell surface is normal. If the mutation of CFTR protein happens the balance of Cl- and fluids is disrupted, causing mucus in various organs to become thick and gluey. As a result, lung infections and, eventually, respiratory failure in the lungs might occur. Mutations on the CFTR normally change single amino acids in the CFTR protein which happens in abnormal channel breaks down soon after it is made.
Explanation:
The CFTR gene gives direction for producing a protein called the cystic fibrosis trans membrane conductance regulator. This protein functions being a channel over the membrane of cells that produce mucus, sweat, saliva, tears, and digestive enzymes.The channel transports negatively filled particles called chloride ions into and out of cells.The transport of chloride ions improves control the movement of water in tissues, which is essential for the creation of thin, freely flowing mucus. Mucus is a slippery substance that greases and defends the lining of the airways, digestive system, reproductive system, and different organs and tissues.The CFTR protein further regulates the role of other channels, such as those that transport positively charged particles called sodium ions across cell membranes. These channels are essential for the normal function of organs such as the lungs and pancreas.
The CFTR protein is involved in regulation of chloride and fluid transport across the cell membrane and in thin mucus development.The mutation in this CFTR protein may cause hindrance in these functions.
Further Explanation:
The cystic fibrosis transmembrane conductance regulator is the protein transcribed by the CFTR gene which acts as the channel protein across the cell membrane which is involved in the production of tears, sweat, saliva and digestive enzyme.
This channel is plays key role in the transport of the negatively charged particles known as chloride ions inside and outside of the cell. This transport regulates the water movement in the tissues and is also required for production of freely flowing, thin mucus. Mucus is little slippery substance which protects and lubricates the airways lining, digestive system and reproductive system.
The CFTR protein also controls other channels function like the one which is involved in the transport of positively charged particle such as sodium ions across the cell membrane.
Cystic fibrosis is caused because of mutation of CFTR gene which may cause either lack of formation of CFTR or malformed CFTR formation. In an individual there are two copies of CFTR gene and for that person to develop CFTR there has to be mutation in both the genes present
Learn more:
- Learn more about disease https://brainly.com/question/1062663
- Learn more about CFTR https://brainly.com/question/1901841
- Learn more about genetic code https://brainly.com/question/4037964
Answer Details:
Grade: College Biology
Subject: Biology
Chapter: Diseases
Keywords:
Cystic fibrosis, transmembrane, conductance regulator, protein, CFTR gene, channel protein, cell membrane, digestive enzyme, negatively charged particles, chloride ions , mucus, reproductive system, mutation.
