Assuming you mean the binomial coefficients
n[tex]C_{r}[/tex] = (n !)/(r!(n - r)!)
10[tex]C_{4}[/tex] = 10!/(4!× 6!) =(10 × 9 × 8 × 7)/(4 × 3 × 2 × 1) = [tex]\frac{5040}{24}[/tex] = 210
4[tex]C_{2}[/tex] = (4!)/(2! × 2!) = [tex]\frac{4.3}{2}[/tex] = 6
product = 210 × 6 = 1260