Answer: long-term governments should not be changed lightly, letter "C".
Explanation: people tend to fear the unknown, and changing means stepping into the unknown. When it comes to government it is even important maintaining a certain status quo, because every nation must have a long-term plan.
A very good example of this is Dom Dinis, king of Portugal in 1279. He ordered his people to plant many trees, foreseeing that Portugal was going to rule the seas. He wasn't alive when the great navigations of his kingdom happened, but the trees he ordered to plant were put to very good use when the ships were built. That is what a long-term plan is, and that can not happen if governments and rules are changed constantly.
However, the text says to not tolerate absolute despotism, so there will be times when we need to act, and these times are when a government does not plan. When there are no plans, our future is at stake.
Therefore, it is important not to change governments for any meanness, meaningless or pesky reason; this is a very important decision and it must happen when absolutely necessary.