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Kana81
Disruption of Homeostasis. Many homeostatic mechanisms keep the internal environment within certain limits (or set points). When the cells in your body do not work correctly, homeostatic balance is disrupted. These factors together influence the body's ability to maintain homeostatic balance. So, yes it can. This is why.
Diseases That Disrupt Homeostasis. ... Insulin dependent diabetes mellitus (IDDM) is a disease that severely affects homeostasis. It is an autoimmune disease, meaning the body is attacking itself. Insulin-producing cells in the pancreas are killed, so there is no insulin available in the blood.

So, there's your answer :D Hope this helps you!