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double-stranded DNA molecule is being transcribed, only part of which is shown below. If the molecule is translated from left to right, one of the nucleotides shown in bold would be the first transcribed in this small molecule. 5'-ATGATCGGATCGATCCAT-3' 3'-TACTAGCCTAGCTAGGTA-5' Which of the following is the correct mRNA produced from the transcription of this DNA molecule?

a. -3'-UACUAGCCUAGCUAGGUA-5'

b. -5'-UACUAGCCUAGCUAGGUA-3'

c. -3'-AUGAUCGGAUCGAUCCAU-5'

d. -5'-AUGAUCGGAUCGAUCCAU-3'

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Answer:

d. -5'-AUGAUCGGAUCGAUCCAU-3'

Explanation:

Transcription is the first step of gene expression. It is a process in which mRNA is produced from the DNA which acts as a template. Enzyme involved in transcription is RNA polymerase. Only one strand of DNA is used as a template and it is the one with 3'-5' direction. So, this means that the synthesized mRNA has the 5'-3' direction. This is because RNA polymerase has the ability to add nucleotides only to 3' end.

Transcription is a highly regulated process, performed in the nucleus of the cell (in eukaryotes).

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