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Interphase: -the cell replicates its chromosomes -each chromosome has two sister chromatids held together by a centromere Prophase 1 chromosomes coil up and a spindle forms -homologous chromosomes come together matched gene by gene forming a tetrad -Crossing Over may occur when chromatids exchange genetic material -this occurs two or three times per pair of homologous chromosomes -Crossing Over results in new combinations of alleles on a chromosomes Metaphase 1: -the centromere of each chromosome becomes attached to a spindle fiber -the spindle fibers pull the tetrads to the equator of the spindle -homologous chromosomes are lined up side by side as tetrads Anaphase 1: -homologous chromosomes separate and move to opposite ends of the cell -centromeres do not split -this ensures that each new cell will receive only one chromosome from each homologous pair Telophase 1: -the spindle breaks down and the chromosomes uncoil -the cytoplasm divides to yield two new cells -each cell has half the genetic information of the original cell because it has only one homologous chromosome from each pair Prophase II- -a spindle forms in each of the two new cells and the fibers attach to the chromosomes Metaphase II- -the chromosomes are pulled to the center of the cell and line up randomly at the equator Anaphase II- -the centromere of each chromosome splits the sister chromatids separate and move to opposite poles Telophase II nuclei re form  the spindles break down  the cytoplasm divides identical to mitosis (Meiosis II) What Meiosis produces four haploid sex cells from one original diploid cell each haploid cell contains one chromosome from each homologous pair haploid cells will become gametes transmitting genes to offspring

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