Answer:
The correct order is:
4. Mesenchymal cells aggregate.
2. Osteoblasts differentiate within mesenchymal connective tissue.
1. Clusters of osteoblasts form osteoid that becomes mineralized.
3. Spicules of bone radiate out from the ossification centers.
Intramembranous Ossification is the Process by which the flat bones of the skull are formed, also contributing to the growth in thickness of the long bones.
The osteblasts synthesize the bone matrix that soon calcifies, trapping them, being now called osteocytes, thus forming irregular bone plates that gradually grow and fuse.
On the inner surface of the cranial bones, there is the activity of osteoclasts, which reabsorb the bone matrix, allowing the brain to grow. At the same time, on the external surface, osteoblasts produce calcified bone matrix, maintaining the thickness of the bone.
With this information, we can conclude that the right order is:
2. Osteoblasts differentiate within mesenchymal connective tissue.
1. Clusters of osteoblasts form osteoid that becomes mineralized.
3. Spicules of bone radiate out from the ossification centers.
4. Mesenchymal cells aggregate.
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