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Which of the following statements concerning the enzyme, telomerase, is true? (Select all that apply.) A) Telomerase removes telomeres, making DNA replication more efficient. B) Telomerase is a ribonuclear protein containing a section of RNA complementary to the telomere. C) Telomerase is reactivated in cancer cells, contributing to their immortality. D) If telomerase was inactivated DNA synthesis would stop.

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Answer:

B) Telomerase is a ribonuclear protein containing a section of RNA complementary to the telomeres

C. telomerase is reactivated in cancer cells, contributing to their immortality

Explanation:

  • Telomerase elongates telomere ends
  • Telomerase binds to a RNA molecule containing  a sequence complementary to the telomeric repeat.
  • Telomerase is usually not active in somatic cells but is active in cancer cells- the protein acts to extend the shortened telomeres in these cells preventing them from dying

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