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A ligand can bind to two receptors, A and B. The Kd for receptor A is 0.001 nM and the Kd for receptor B is 1 nM. Based on the equation below, if the ligand concentration is 0.1 nM, which receptor will have the highest percentage bound to a ligand?

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Answer:

The answer is: Receptor A because the ligand concentration is greater than the Kd.

Explanation:

Receptor A because the ligand concentration is greater than the Kd., because the conformation of a receptor protein composes the functional state. Ligands include substrates, inhibitors, activators, and neurotransmitters. So, Affinity is a measure of the strength of attraction between a receptor and its ligand.

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