For a given population, consider a gene locus in HWE with two alleles labeled O and U. If the U allele occurs in the population with a frequency of 0.44, then: A. The heterozygote frequency is 0.493. B. The heterozygote frequency is 0.194. C. The UU genotype frequency is 0.314. D. The O allele frequency is 0.66. E. All genotype frequencies cannot sum to 1.00.