Answer:
Double stranded RNA may affect gene expression negatively
Explanation:
Double stranded RNA are molecules that can affect negatively the gene expression by the fact that this kind of molecule can be complementary to others RNA molecules, or also to DNA regions on the genome. Therefore, introducing such molecules in mammalian cells can inactivate the transcription of a specific gene by the fact that those molecules could block regions of the genome that code for a gene or by connecting to some RNA molecules by similarity. Such mechanisms will reduce the production (or expression) of a given protein in these cells.