Explain why the change in the way that molecules of b globin interact with each other lead to the sickling of the red blood cells in sickle cell anemia

Respuesta :

The sickle form of the hemoglobin gene is created when an adenine nucleotide is changed to a thymine. ... That single amino acid replacement in the -globin protein alters the shape and the chemistry of the hemoglobin molecule, causing it to polymerize and distort the red blood cell into the sickle shape.