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A client presents for a scheduled Papanicolaou (Pap) smear. The clinician who will interpret the smear will examine cell samples for evidence of:

A) Changes in cell shape, size, and organization
B) The presence of unexpected cell types
C) Ischemic changes in cell samples
D) Abnormally high numbers of cells in a specified field

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KerryM

Answer:

A) Changes in cell shape, size, and organization

Explanation:

Changes in cell shape, size and organisation suggests that a population of cells have changed identity. This could indicate the presence of mutations in the DNA that could lead to uncontrolled cell proliferation or abnormal cell types. These are indicative of tumorigenesis and potential pre-cancerous cells.

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