A long-term weakness of the Missouri Compromise is that the fundamental disagreement about slavery was not resolved.
Why did the Missouri Compromise fail?
The Missouri Compromise did not succeed in tackling the problem of slavery because it widened the divisions between the Northern and Southern states.
Instead of solving the problem of slavery in new territories, Congress intensified the tensions between the North and South.
Thus, The correct statement is Option C. that is the fundamental disagreement about slavery was not resolved.
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