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When an appropriate signal binds to a G protein-coupled receptor, what is the best description of how the information is passed across the plasma membrane?

Choice A., Binding of the signal molecule triggers the cell to produce G protein.
Choice B., The signal molecule is transported across the plasma membrane by the receptor protein.
Choice C., Signal binding causes a conformational change in the cytoplasmic portion of receptor protein.
Choice C., Signal binding causes a conformational change in the cytoplasmic portion of receptor

Respuesta :

Answer:

Signal binding causes a conformational change in the cytoplasmic portion of receptor protein

Explanation:

G-protein coupled receptors or GPCR are one of the most abundant and most common receptors present in the human body which sense a variety of stimulus from the environment.

These GPCR are located on the surface of the cell in the plasma membrane seven times and are thus called seven-transmembrane receptors.

The  GPCR is associated with a G protein complex and when a ligand or stimulus binds to the receptors they cause a conformational change towards the cytoplasmic side. This conformational change transfers the GDP to G protein and a cascade of the signal begins.

Thus, the selected option is correct.

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