tamara1701
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What if a mutation occurred in the human insulin gene and the first codon was changed to CCG? Is
this a silent mutation? Explain how you know.

Respuesta :

Yes, this will be a silent mutation.

Explanation:

The mutation which occurred in the human insulin gene where the first codon was changed to CCG will be a silent codon because this will not change the sequence of the amino acid and the amino acids formed will remain the same.

A silent mutation occurs due to base substitutions resulting in a change in the nucleotide that does not impact the amino acid or protein formed once the mRNA is translated. The protein will retains its functional aspects.

marianaegarciaperedo

The point mutation occurs in only one base. Silent mutations are point mutations that code for the same amino acid as the original codon. In the exposed example, it is a silent mutation.

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The mutation would still code for the same amino acid, meaning that it is a silent mutation.

When a change occurs in a single base pair, it is known as a point mutation.

Points mutations might be either silent, missense, or nonsense.

  • In silent mutations, the resulting mRNA codon codes for the same amino acid as the unmutated sequence.

  • However, if the mutation causes the mRNA codon to code for a different amino acid, this mutation is a missense mutation.

  • Finally, if the mutation causes mRNA codon to be a stop codon, we are referring to a nonsense mutation.

In this example, the mutation is a point mutation, and the mutated base causes no change in the amino acid codification. So the protein remains the same.

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