5000 Thailand natives were tested for their MN blood grouping. This allele has incomplete dominance and analysis indicated a phenotypic distribution of 600M, 4000MN, 400N. What is the frequency of the N allele?

Respuesta :

Answer:

0.28

Explanation:

This allele has incomplete dominance and analysis indicated a phenotypic distribution of 600M, 4000MN, 400N.

Using p+q = 1

Where q is the frequency of the N allele-

400N/5000 = 0.08 is the genotypic frequency out of 5000 in total - q²

Thus the frequency of the allele N is √q² = √0.08 = 0.28

The frequency of the N allele is 0.48

What is incomplete dominance?

Incomplete dominance occur when a progeny of a particular parents gives or have a phenotype that combines both parents gene.

This phenotype is intermediate of the two parents and often unique.

Total population of Thailand= 5000

Allele P= 600M

Allele pq= 4000MN

Allele Q= 400N

According to hardyweingberg principles,

P+Q= 1

p2+2pq+q2=1

Therefore, to calculate frequency of allele N in the population we have;

N for Q= 400/5000=0.08

N for pq= 4000/5000=0.8

since pq contain both allele q and p in equal proportion we have

N for pq= 0.5*0.8 = 0.4

Frequency of N in allele N and MN is

0.08+ 0.4 = 0.48.

Therefore, the frequency of the N allele is 0.48

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