Calculate the fractional saturation for hemoglobin when the partial pressure of oxygen is 40 mm Hg. Assume hemoglobin is 50%% saturated with oxygen at a partial pressure of 22 mm Hg and that the Hill coefficient is 3.

Respuesta :

Answer:

The fractional saturation for hemoglobin is 0.86

Explanation:

The fractional saturation for hemoglobin can be calculated using the formula

[tex]Y_{O_{2} } = \frac{(P_{O_{2} })^{h} } {(P_{50})^{h} + (P_{O_{2} })^{h} }[/tex]

Where [tex]Y_{O_{2} } \\[/tex] is the fractional oxygen saturation

[tex]{P_{O_{2} }[/tex] is the partial pressure of oxygen

[tex]P_{50}[/tex] is the partial pressure when 50% hemoglobin is saturated with oxygen

and h is the Hill coefficient

From the question,

[tex]{P_{O_{2} }[/tex] = 40 mm Hg

[tex]P_{50}[/tex] = 22 mm Hg

h = 3

Putting these values into the equation, we get

[tex]Y_{O_{2} } = \frac{(P_{O_{2} })^{h} } {(P_{50})^{h} + (P_{O_{2} })^{h} }[/tex]

[tex]Y_{O_{2} } = \frac{40^{3} }{22^{3} + 40^{3} }[/tex]

[tex]Y_{O_{2} } = \frac{64000 }{10648 + 64000 }[/tex]

[tex]Y_{O_{2} } = \frac{64000 }{74648 }[/tex]

[tex]Y_{O_{2} } = 0.86[/tex]

Hence, the fractional saturation for hemoglobin is 0.86.