1. The Northern colonies were oldest, hence the phrase “The Original Thirteen Colonies.
2. Colonialists, unlike Native Americans, settled by sea on wooden boats and were first coastal (Manhattan, NY by the Atlantic Ocean, Chicago, IL by The Great Lakes, etc.).
3. The North was more industrial, the South more agrarian.
4. During The Civil War, the North opposed the South over slavery, traditionally a more agrarian society. The South lost, and slaves were freed by the Emancipation Proclamation.
Hope this helps!