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Answer:
Cancer is a chronic disease in which cells reproduce abnormally, exceeding the capacity of the body tissues to assimilate such reproduction, which causes alterations in these cells and in the organs they affect.
Therefore, if a sample is required to determine some type of genetic disorder in the patient, non-cancerous cells should be used, since these will contain genetic material free of any alteration caused by said disease and, therefore, will be a test of greater accuracy to determine said disorder.
- The reason why non-cancerous cells is important to test Lee for a genetic disorder instead of the biopsy tissue is that that cancer cells often undergoes mutation in a short timeframe and also does gather a lot.
- So therefore, an individual cannot know if a said mutation has been in the person since birth or otherwise.
It is very essential then to look the genetic makeup to normal cells and compare them to see as it could help in choosing personalized therapy for Lee.
Cancer cell's genes are very unstable in nature and they replicate very fast speed. The use of non cancerous cells will better tell if the cancer is genetic or not when compared to the use of biopsy tissue.
Germline testing is often carried out to know if an individual has a gene mutation that can increase the risk of developing cancers.
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