The city which is most likely to have started as a Spanish mission is: 4. Los Angeles, California (CA).
What is a Spanish mission?
A Spanish mission can be defined as a religious community which comprises a group of people sent by the Roman Catholic Church and Spanish Empire between the 16th and 19th centuries, so as to evangelize and help the people living in North America.
The Spanish missions in California consist of 21 religious missions that were established between 1769 and 1833 in various cities such as:
Read more on Spanish missions here: https://brainly.com/question/539873
