What are TWO reasons that the Louisiana Purchase caused a debate in the United States?

1:People living in rural areas feared that they would be forced to move west.

2: The Louisiana Purchase exposed the United States to the risk of a Spanish invasion.

3:Many politicians felt that the US Constitution did not allow such a purchase.

4: Military leaders believed that defending the new territory would be a burden.

5: Some politicians accused President Thomas Jefferson of acting against his own principles.

I believe one of them is 3 does anyone know that the other one is?? Thx