Using the chart, which of the following point mutations will cause the most harmful effect on an individual?
A. The sequence reads AUU; a change in the second base from U to C
B. The sequence reads CGA; a change in the first base from C to A
C. The sequence reads UGU; a change in the third base from U to A
D. The sequence reads UUA; a change in the first base from U to C and a change in the third base from A to G
