The Tuskegee Syphilis Study is an infamous clinical study conducted by the U.S. Public Health Service to study the progression of untreated syphilis in poor black men in Alabama. This experiment took place between 1932 and 1972 and tricked participants into thinking they were receiving free health care from the government. The participants were unaware they would be infected with syphilis and left untreated. After a leak to the press, the experiments stopped, the Office for Human Research Protections was established, and federal laws were put in place that required Institutional Review Boards for studies that involve human subjects.
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