The physical property that will be different between the two is density while their chemical properties are the same because they have the same number of valence electrons.
Isotopes refers to atoms of the same element that has the same atomic number but different mass numbers. Isotopes only differ in the number of protons present in each isotope.
One physical property that is different in the isotopes 63Cu and 65Cu is density. Recall that density is a bulk property. The density of 65Cu is greater than that of 63Cu. Their chemical properties are the same because the both atoms have the same number of valence electrons.
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