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Using the division operation, the set of number of in which the larger number is about 20 times greater than the lesser number is depicted by the options C and D.

Evaluating each set of number :

1.)

[tex]\frac{2.01 \times 10^{7}}{4.25 \times 10^{6}} = 4.73 [/tex]

2.)

[tex]\frac{4.91 \times 10^{6}}{5.09 \times 10^{3}} = 964.64 [/tex]

3.)

[tex]\frac{8.21 \times 10^{-3}}{4.13 \times 10^{-4}} = 19.88 [/tex]

4.)

[tex]\frac{5.97 \times 10^{4}}{3.12 \times 10^{3}} = 19.13[/tex]

Therefore, the set of numbers which shows a number being about 20 times greater than the other are options C and D

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