6.34 Prenatal vitamins and Autism: Researchers studying the link between prenatal vitamin use and autism surveyed the mothers of a random sample of children aged 24 - 60 months with autism and conducted another separate random sample for children with typical development. The table below shows the number of mothers in each group who did and did not use prenatal vitamins during the three months before pregnancy (periconceptional period). (Schmidt, 2011)
Autism Typical Development Total
No vitamin 111 70 181
Vitamin 143 159 302
Total 254 229 483

(b) Complete the hypothesis test and state an appropriate conclusion.
What is the value of the test statistic for this test? ____ (Please round to two decimal places) What is the p-value associated with this test? _____ (Please round to four decimal places)

Respuesta :

The test is to find out if there is a difference in the proportion of the number of autism in two samples differentiated by the use of vitamins.

The test statistic for the test is approximately 2.98

The p-value associated is 0.0028

Reasons:

The given parameters are;

[tex]\begin{array}{|l|c|c|c|}&\mathbf{\underline{Autism}}&\mathbf{\underline{Typical \ Development }}&\mathbf{\underline{Total}}\\No \ vitamin&111&70&181\\Vitamin&143&159&302\\Total&254&229&483\end{array}\right][/tex]

The null hypothesis is H₀; [tex]\hat{p}_1 = \hat{p}_2[/tex]

The alternative hypothesis is Hₐ; [tex]\hat{p}_1 \neq \hat{p}_2[/tex]

Where:

[tex]\hat{p}_1[/tex] = The proportion of the sample that did not use vitamin and had autism

[tex]\hat{p}_2[/tex] = The proportion of the sample that used vitamin and had autism

The test statistics for the difference of two proportions is given as follows;

[tex]Z=\dfrac{\hat{p}_1-\hat{p}_2}{\sqrt{\hat{p}\cdot (1-\hat{p}) \cdot \left (\dfrac{1}{n_{1}}+\dfrac{1}{n_{2}} \right )}}[/tex]

Where;

n₁ = 181, n₂ = 302, [tex]\hat p_1 = \dfrac{111}{181}[/tex],  [tex]\hat p_2 = \dfrac{143}{302}[/tex], [tex]\hat p = \dfrac{111 + 143}{181 + 302 } = \dfrac{254}{283}[/tex]

[tex]The\ test\ statistics,\, Z=\dfrac{\dfrac{111}{181}-\dfrac{143}{302}}{\sqrt{ \dfrac{254}{283}\cdot (1-\dfrac{254}{283}) \times \left (\dfrac{1}{181}+\dfrac{1}{302} \right )}} \approx 2.98[/tex]

The test statistic for the test, Z ≈ 2.98

From the Z-table, we have Z > 2.98 = 1 - 0.9986, therefore, given that the

alternative hypothesis [tex]\hat p_1 \neq \hat p_2[/tex], the p-value is 2 × (1 - 0.9986) = 0.0028

The p-value associated with the test is 0.0028

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