When the inside of the membrane becomes less negative, the membrane potential is said to be DEPOLARIZATED. Hyperpolarization is the inverse flow of electrochemical charges.
Depolarization and hyperpolarization of the membrane occur when specific ion channels open or close.
Depolarization occurs when the potential of the membrane becomes more positive (i.e. less negative).
A stimulus can produce the opening of ion channels, thereby positive ions flow inside the cell and thus trigger depolarization.
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