The published data for the map distance between the gene and the centromere is 26 map units. You just calculated the map distance as 17 map units. What is the best explanation for this disparity

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catscute4967 catscute4967

24-11-2021
Biology

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The published data for the map distance between the gene and the centromere is 26 map units. You just calculated the map distance as 17 map units. What is the best explanation for this disparity

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luisvaschetto luisvaschetto · Answer 1 · 2021-12-07T10:04:29+01:00

Linkage maps and physical maps are NOT the same. A linkage map measures the number of recombination events in a given chromosome fragment.

A linkage map is based on the frequency of recombination events between genes or molecular markers.

This frequency indicates the number of events in which a single chromosomal fragment recombines between two or more genes or molecular markers during meiosis.

Conversely, a physical DNA map indicates the physical locations of genes (molecular markers) and nucleotide (DNA) sequences of interest, which is useful to identify genes by positional cloning.

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