What do you notice is different in the sarcomere of a person with DMD compared to a person without DMD? What role do you think dystrophin plays in this difference?

Respuesta :

The sarcomere of a person with DMD is different from a normal person because in individuals suffering DMD the sarcomere can not contract properly. It is due to mutations in the dystrophin gene.

Duchenne muscular dystrophy

The sarcolemma refers to the functional and structural contractile unit of the myofibril in a muscle cell.

Duchenne muscular dystrophy (DMD) is a degenerative disease caused by mutations in a gene that encodes a protein called dystrophin.

Dystrophin is fundamental for the formation of a protein complex that binds the cytoskeleton of a given muscle cell to its extracellular matrix.

Dystrophin is associated with the complex between the sarcolemma and myofilaments observed in the muscle fibers.

Learn more about Duchenne muscular dystrophy here:

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