A single change or alteration in the nucleotide base of the genetic material of the cell is called a point mutation. It can be a deletion, addition or inversion of a single nucleotide base.
In the following, the mutations that occurred are 1. C and 2. B.
How the mutation can be explained?
- Silent mutation occurs in a single base of the triplet codons of the bases but the alterations do not cause an observable effect and they remain as a neutral alteration. They do not affect the function of the protein. Thus, the glycine to glycine is a silent mutation.
- Non-sense mutations are caused when the single change in the nucleotide base results in the formation of the stop codon. Thus, lysine to stop codon is a nonsense mutation.
Therefore, silent and nonsense mutations are the correct options.
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