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Berryo

'Water freezes at 0 degrees C' is a universal truth, meaning that it is a statement accepted as a general truth.

In making this statement negative, we could say that:

Water doesn't freeze at 100 degrees C. Water freezes at 0 degrees C.

Or, the verb 'freezes' could be replaced by the negative form of its antonym which is 'boils'.

Water doesn't boil at 0 degrees C. Water boils at 100 degrees C.