Some medications are formulated such that there is a slow release of active ingredients. Such formulations are known as "extended release." Azithromycin ER is a single-dose, extended release formulation. The recommended dosage for a child 6 months and older who is brought to the emergency room with community acquired pneumonia is 60 mg/kg administered orally. Azithromycin (immediate release) has much faster onset of action and acts almost immediately when administered intravenously (by IV). Clinicians exercise clinical judgement when deciding whether or no to treat a pediatric patient with azithromycin intravenously. If therapy is deemed necessary, a dose of 10 mg/kg for those aged 6 months to 16 years is considered reasonable. How does the appropriate dose of azithromycin ER for a baby weighing 7.7 kg such as Amaan compare with the dose of azithromycin that was given intravenously to Amaan?​

Respuesta :

Based on the dosage of each drug, the amount of azithromycin ER is 375 mg greater than intravenous Azithromycin for a 7.7 kg baby.

What is drug dosage?

The dosage of a drug is the amount of drug required to treat a particular disease per body weight of an individual.

The dosage of azithromycin ER for treatment of pneumonia is 60 mg/kg administered orally.

Dosage of intravenous Azithromycin is 10mg/kg

For a 7.7kg baby:

Amount of azithromycin ER = 7.7 kg × 60 mg/kg = 462 mg

Amount of intravenous Azithromycin = 7.7 mg × 10 mg/kg = 77 mg

Difference between the two amounts = 375 mg

There, the amount of azithromycin ER is 375 mg greater than intravenous Azithromycin for a 7.7 kg baby.

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