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PKU and albinism are two autosomal recessive disorders,unlinked in human beings. if couple each of them heterozygous for both traits, produce a child, what is the chance of their having a child with (a)PKU (b)albinism (c)both traits?

Respuesta :

A. multiply the chance that it will be a boy x the chance he will have PKU (1/2 x 1/4) 

B. chance of having PKU + chance of albinism 

C. chance PKU x chance albinism

Answer:

a) 3/16; b) 3/16; c) 1/16

Explanation:

PKU and albinism are two autosomal recessive disorders. The possible genotypes and phenotypes for each disease are:

PKU

  • PP: normal
  • Pp: normal
  • pp: PKU

Albinism

  • AA: normal
  • Aa: normal
  • aa: albinism

If a couple of individuals heterozygous for both genes (PpAa) has offspring, from the Punnett Square we get the chances of them having:

a) PKU only

ppA_: 3/16

b) Albinism only

P_aa: 3/16

c) both traits

ppaa: 1/16

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