The main two requirements to compare the energy for 2 compounds are the balanced chemical formula and the temperature of the compounds.
Gibb's free energy change of any reaction will be calculated by using the below equation as:
ΔG = ΔH - TΔS, where
ΔH = change in enthalpy
T = temperature
ΔS = change in entropy
Before calculating the free energy of any reaction you should first balance the given chemical reaction to check the involved moles of substance and also the value of temperature before & after the completion of reaction to check the nature of the reaction.
Hence balancing the equation and checking the temperature are the two requirements.
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