During endochondral bone formation, the epiphyses remain cartilaginous until the stage of adulthood.
What does endochondral generation mean?
Endochondral generation is a cellular phenomenon where hyaline cartilage can be replaced with bones.
This phenomenon (endochondral formation) is due to the differentiation of specialized mesenchymal cells to chondrocytes.
Endochondral formation of bones includes:
- mesenchymal cells
- differential gene expression (chondrocytes)
- proliferation
- bone formation
In conclusion, during endochondral bone formation, the epiphyses remain cartilaginous until the stage of adulthood.
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