The appropriate options regarding the quotation given by adam Smith are either option 1 or 3.
Anything done with the intent to benefit oneself is self-interest. Self-interest can be shown, for instance, in the pursuit of greater education in order to land a better job and earn more money down the road.
Self-interest, according to Smith, is a human instinct. That much is evident from the quotation above, where he claims that "every man" is "by nature" preoccupied with "his own care."
Hence, options 1 and 3 both are correct from point of the view of adam smith.
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