The steps of the mechanism and development of an immediate (Type I) allergic reaction are as follows:
- Individual is exposed to as sensitizing dose of allergen
- Cells produce IgE directed against the allergen
- IgE coats (sensitizes) mast cells and basophils
- A provoking exposure to the allergen occurs and mast cells and basophils degranulate releasing histamine and other allergic mediators
- Individual experiences allergy symptoms
What is type 1 allergic response?
Type 1 allergic reaction is known as immediate allergic response because it occurs within a short time of exposure to allergen.
It involves immunoglobulin E, IgE.
The steps of the mechanism and development of an immediate (Type I) allergic reaction are as follows:
- Individual is exposed to as sensitizing dose of allergen
- Cells produce IgE directed against the allergen
- IgE coats (sensitizes) mast cells and basophils
- A provoking exposure to the allergen occurs and mast cells and basophils degranulate releasing histamine and other allergic mediators
- Individual experiences allergy symptoms
In conclusion, Type 1 allergic reaction is an immediate allergic response.
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