Predict the major product for the following transformation, and propose a mechanism for its formation: 21.08a1

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21-07-2022
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Predict the major product for the following transformation, and propose a mechanism for its formation: 21.08a1

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azikennamdi azikennamdi · Answer 1 · 2022-08-02T12:54:21+02:00

The correct product of the transformation derives from the process of alpha halogenation after which there is and E2 elimination. See the attached.

What is Alpha Halogenation?

A useful reaction to add leaving groups at the alpha position for subsequent substitution or elimination reactions is alpha halogenation.

Alpha halogenation can occur in basic or acidic environments. See Step I and Step II of the halogenation process attached.

What are the types of halogenation?

Halogenation reactions may be divided into two categories:

(A) substitution processes, in which the halogen replaces another atom in the molecule, such as when ethane is chlorinated, and

(B) addition reactions, in which the halogen combines with an unsaturated molecule.

Learn more about alpha halogenation:
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