The probability that at least 8 patients show improvement is; 0.94
The formula for Binomial Probability Distribution is;
P(X = r) = nCr * p^(r) * (1 - p)^(n - r)
where;
n = number of trials
r = number of specific events you wish to obtain
p is probability of success
From the question, we have;
n = 12
r = 8
p = 81% = 0.81
The probability that at least 8 patients show improvement is expressed as;
P(X ≥ 8) = P(X = 8) + P(X = 9) + P(X = 10) + P(X = 11) + P(X = 12)
Using online binomial probability calculator gives us;
P(X ≥ 8) = 0.11954 + 0.22649 + 0.28967 + 0.22453 + 0.07977
P(X ≥ 8) = 0.94
Read more about Binomial Probability Distribution at; https://brainly.com/question/15246027
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