Their DNA polymerase has compromised 3' to 5' exonuclease function.
An enzyme that builds lengthy nucleic acid or polymer chains is called a polymerase. Using base-pairing interactions to copy a DNA template strand, DNA polymerase and RNA polymerase build DNA and RNA molecules, respectively, while half ladder replication builds DNA molecules.
For the polymerase chain reaction, a crucial molecular biology method, the thermophilic bacteria Thermus aquaticus' DNA polymerase is used. Template dependence or independence are two possible states for a polymerase. Template independent polymerase examples include poly-A-polymerase. Both template independent and dependent activity are known to exist for terminal deoxynucleotidyl transferase.
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