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Increase in carbon dioxide in your red blood cells, which causes a drop in pH, causes your breathing to speed up.

The presence of  carbon dioxide in red blood cell will lower the pH because  carbon dioxide combines with water to form [tex]H^{+}[/tex] and [tex]HCO_{3} ^{-}[/tex] .

  • About 70% of Carbon dioxide transported as bicarbonate ion in the plasma of the red blood cells .
  • When carbon dioxide diffuses across the cell membrane of erythrocyte then it reacts with water to form carbonic acid.
  • This carbonic acid breaks into bicarbonate ion and proton  in the presence of carbonic anhydrase . this is because it is very unstable.
  • This hydrogen ions binds to the hemoglobin and which results in initiation of bohr effect .
  • So, as concentration of hydrogen ions increases pH of the blood decreases.

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