Cytotoxic t-cells are able to recognize infected body cells because the infected cells display foreign antigens.
The helper T cell and the cytotoxic T cell are the two main subtypes of T cells. Helper T cells, as their names imply, "assist" other immune system cells, whereas cytotoxic T cells "kill" virally-infected cells and tumors. The TCR cannot directly bind antigen, unlike an antibody.
Killer T cells are also known as "cytotoxic" or "cytolytic" cells because they have unique molecular weapons that allow them to attack and kill other cells that are showing targets they are familiar with, such as a virus-infected cell or even a malignant cell. The processed cancer cell antigen, which is solely presented by MHC-class I, must be recognized by cytotoxic T lymphocytes. Helper T cells binding to a processed antigen on the same dendritic cell as the MHC-class II presenting a processed cancer cell antigen enhances cytotoxic T-cell complete activation.
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