If low affinity is present, no activation takes place and transcription is less.
Transcription factors are proteins that regulate the transcription of genes—that is, their copying into RNA, on the way to making a protein.
Proteins called transcription factors, however, play a significantly central role in regulating transcription. These important proteins help determine which genes are involved in each cell of your body.
Under the impact of transcription factors, the various cells of the body can function differently though they have the exact genome. Transcription factors attach to one or more series sites, which are called transcription element binding sites (TFBSs), binding to specific DNA sequences of the genes they control
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